If you’re taking a GLP-1 medication for weight loss or diabetes management, you’ve probably heard about some of the side effects—like fatigue or loss of muscle mass. The good news is that physical therapy can help you stay strong, mobile, and confident as your body changes.
Understanding GLP-1 Medications and Their Effects
GLP-1 receptor agonists—such as Ozempic®, Wegovy®, Mounjaro®, and Trulicity®—are widely used to help manage diabetes and promote weight loss. These medications work by lowering blood sugar and reducing appetite, supporting healthier eating habits and reduced body weight.
However, when weight loss occurs too quickly or without regular exercise, the body can lose more than fat. It can also lose lean muscle mass and bone density, which are critical for long-term strength and mobility. That’s where physical therapy comes in.
Potential Side Effects of GLP-1 Medications
Many people taking GLP-1 medications notice physical changes that can affect how they move and feel, including:
- Fatigue or decreased endurance
- Muscle weakness or loss of lean mass
- Joint stiffness or tendon discomfort
- Slower metabolism
- Balance changes or increased fall risk
- Digestive symptoms such as nausea or constipation
These side effects don’t mean you need to stop your medication — but they do highlight the importance of maintaining movement, strength, and balance throughout your weight loss journey.
How Physical Therapy Supports Safe, Sustainable Weight Loss
At Lifeline Physical Therapy, we help individuals on GLP-1 therapy maintain strength, prevent muscle loss, and stay active. Our physical therapists create personalized programs designed to:
- Preserve muscle and bone health with targeted strength and resistance exercises
- Improve mobility and flexibility to reduce stiffness and enhance posture
- Boost energy and endurance through progressive movement routines
- Enhance balance and coordination to lower fall risk
- Support whole-body wellness with education and guided exercise strategies
Our goal is to ensure your GLP-1 success is not just about losing weight—it’s about gaining confidence, stability, and lasting health.
A Whole-Person Approach to Wellness
At Lifeline, we understand that better health is more than a number on the scale. Our clinicians combine orthopedic and movement expertise with individualized care to help you stay strong, active, and independent—so you can feel your best at every stage of your journey.
Take the Next Step
If you’re using a GLP-1 medication and want to protect your strength and mobility, we’re here to help. Contact your nearest Lifeline Physical Therapy location to schedule your evaluation today.
